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Drake Jackson, once celebrated as the San Francisco 49ers’ top pick in the 2022 NFL Draft, has become a headline in offseason news. Fans and analysts alike are asking: What led to the 49ers waiving Drake Jackson? Let’s explore his promising start, the injuries that derailed his progress, and what the future may hold for this talented defensive end.
Drake Jackson entered the league with high expectations. As a former USC standout, his athleticism and unique skill set made him a notable second-round pick. In his rookie year, he played 15 games, logging three sacks, three tackles for loss, and eight pass breakups. His dazzling Week 1 performance in the 2023 season, where he tallied three sacks against the Steelers, showcased the potential the 49ers saw in him.
Unfortunately, the momentum didn't last. Midway through the 2023 season, Jackson suffered a significant knee injury. The setback forced him to miss the remainder of that season and sidelined him for the entire 2024 campaign. He underwent major surgery in early 2024, which led to ongoing concerns about his recovery and long-term durability.
As reported by Niners Nation, Jackson's production was impacted by these injuries. Despite his high upside, he saw only 23 games over three seasons, leaving fans and coaches wondering what could have been if not for the health setbacks.
By May 2025, the 49ers made the difficult call to waive Drake Jackson with a failed physical designation. According to CBS Sports, Jackson is expected to be medically cleared by training camp. However, the team chose to give him more time to recover and the opportunity to seek a new home before camp begins.
The 49ers’ 2022 draft class has seen mixed results. Jackson, along with other early picks, never reached the expected impact due to various reasons. Only Brock Purdy, chosen in the seventh round, developed into a regular starter, highlighting the unpredictable nature of the draft process.
Although the 49ers have moved on, the story isn't over for Drake Jackson. If he recovers fully, he could be a valuable addition for another NFL team looking for depth at outside linebacker or defensive end. His youth and talent make him a potential high-upside free agent, provided he returns to form. Those interested in more on the transition can read coverage from NBC Sports, which confirms that Jackson will not be part of the 49ers’ next phase but should be on the radar for teams in need of pass-rushing talent.
Drake Jackson’s journey with the 49ers has been filled with both promise and adversity. While injuries have limited his NFL impact so far, his recovery could open new opportunities. Fans should monitor his progress as Jackson seeks another shot to prove his worth on the field. Will another team take a chance on the once-promising defender? Time will tell.