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The 2025 MLB season brings another exciting showdown as the Chicago Cubs face off against the Miami Marlins. This Cubs vs Marlins series is pivotal for both teams as they look to build momentum in the National League. Let’s dive into what to expect, standout players, updated odds, and predictions for this highly anticipated matchup.
Both teams are coming off notable stretches. Since their last meeting, the Cubs swept the White Sox, finding their rhythm at home. In contrast, the Marlins secured a solid series win against the Rays. These performances set the stage for a competitive Cubs vs Marlins series. According to the Bleed Cubbie Blue series preview, this brief six-game stint between the two teams in a 10-day span is rare, and the Cubs have a historical .517 winning percentage against the Marlins.
Probable Pitching Matchups:
Game times are 5:40 p.m. CT on Monday and Tuesday, and 12:10 p.m. CT on Wednesday—all available on Marquee Sports Network.
One major storyline in this Cubs vs Marlins series is the emergence of young talent on both rosters. For the Cubs, Pete Crow-Armstrong is drawing attention with his power and steady offense. According to expert predictions from Action Network, Crow-Armstrong is positioned for a breakout, boasting a 14.3% barrel rate and a high fly-ball percentage. Meanwhile, Miami has seen promising developments from Kyle Stowers and Agustín Ramírez in their lineup, providing much-needed offensive spark.
The upcoming slate promises tight contests, with odds makers favoring Chicago in the early games. On Monday, the Cubs hold a -175 moneyline edge, while the Marlins come in at +145. Over/under for the first game sits at 9 runs, according to current odds and picks by FOX Sports.
Expert picks highlight Pete Crow-Armstrong as a top candidate to hit a home run in the series opener, showcasing his upward trajectory in 2025. Miami’s pitching has struggled with high walk rates and low fastball usage, which could tilt the matchup in favor of Chicago’s hitters. Still, the Marlins have proven resilient, especially late in games and against relievers.
The Cubs and Marlins have traded victories in recent years, creating a balanced rivalry. Notably, the Cubs have outscored the Marlins by more than 100 runs all-time (1,089 to 982). At loanDepot park, the matchup is nearly even, making this series even more unpredictable. The unique scheduling quirk—seeing the teams meet twice in three series—adds another layer of intensity.
The Cubs vs Marlins series will test both teams’ rotations and showcase young stars eager to make their mark. While Chicago appears to be slight favorites, Miami's unpredictable offense means anything can happen across these three games. Fans should look forward to tight games, developing storylines, and must-watch performances on both sides.
Dive deeper with the comprehensive series preview on Bleed Cubbie Blue and detailed betting analysis from Action Network.
Stay tuned as the action unfolds in this classic Cubs vs Marlins chapter!